Diphenylcarbodiimide, tshuaj formula2162-74-5, yog ib qho kev sib xyaw uas tau nyiam ntau yam hauv thaj chaw ntawm cov organic chemistry. Lub hom phiaj ntawm tsab xov xwm no yog muab cov ntsiab lus ntawm diphenylcarbodiimide, nws cov khoom, kev siv, thiab qhov tseem ceeb hauv ntau daim ntawv thov.

Diphenylcarbodiimide yog ib qho sib xyaw nrog cov mis molecular C13H10N2. Dawb mus rau dawb crystalline khoom, me ntsis soluble nyob rau hauv dej, yooj yim soluble nyob rau hauv acetone, ethanol, chloroform thiab lwm yam organic solvents. Qhov sib xyaw no paub zoo tshaj plaws rau nws lub peev xwm los ua ntau yam reagent hauv cov organic synthesis, tshwj xeeb tshaj yog nyob rau hauv kev tsim ntawm amides thiab ureas.

Ib qho ntawm cov khoom tseem ceeb ntawm diphenylcarbodiimide yog nws cov reactivity nrog amines thiab carboxylic acids, ua rau tsim cov amides. Cov tshuaj tiv thaiv no yog hu ua carbodiimide coupling cov tshuaj tiv thaiv thiab yog siv dav hauv peptide synthesis thiab biomolecule hloov kho. Tsis tas li ntawd, diphenylcarbodiimide tuaj yeem cuam tshuam nrog cawv los ua polyurethane, ua rau nws muaj txiaj ntsig zoo hauv kev tsim cov khoom siv polyurethane.

Hauv kev lag luam kws tshuaj, diphenylcarbodiimide tuaj yeem siv los ua ke ntau yam tshuaj thiab tshuaj intermediates. Nws lub peev xwm los txhawb kev tsim cov ntawv cog lus amide yog qhov muaj txiaj ntsig tshwj xeeb rau kev txhim kho cov tshuaj peptide thiab bioconjugates. Tsis tas li ntawd, qhov sib xyaw ua ke ua rau muaj kev cuam tshuam rau carboxylic acids ua rau nws muaj txiaj ntsig zoo rau kev sib txuas cov tshuaj rau lub hom phiaj molecules, yog li ua kom tsim cov tshuaj xa mus rau cov tshuaj.

Ntxiv nrog rau lawv lub luag haujlwm hauv cov organic synthesis, diphenylcarbodiimides tau kawm rau lawv cov peev txheej siv hauv cov ntaub ntawv tshawb fawb. Lub compound lub reactivity ntawm alcohols ua rau nws pab tau nyob rau hauv zus tau tej cov polyurethane foams, coatings thiab adhesives. Nws lub peev xwm los tsim polyurethane ua rau nws yog ib qho tseem ceeb hauv kev tsim cov khoom siv ruaj khov, ntau yam polyurethane siv nyob rau hauv ntau yam kev lag luam los ntawm kev tsim kho mus rau tsheb.

Qhov tseem ceeb ntawm diphenylcarbodiimides txuas mus rau hauv thaj chaw ntawm bioconjugation thiab bioorthogonal chemistry. Nws reactivity rau biomolecules tau siv rau qhov chaw tshwj xeeb kev hloov pauv ntawm cov protein thiab nucleic acids, ua rau kev txhim kho cov bioconjugates tshiab thiab bioimaging probes. Tsis tas li ntawd, qhov sib xyaw ua ke nrog cov dej nyob ib puag ncig ua rau nws muaj txiaj ntsig zoo rau kev tsim cov tshuaj tiv thaiv bioorthogonal los kawm txog cov txheej txheem lom neeg hauv lub neej.

Nyob rau hauv cov ntsiab lus, diphenylcarbodiimide, tshuaj formula 2162-74-5, yog ib tug multifunctional compound nrog ntau yam kev siv nyob rau hauv lub teb ntawm organic synthesis, kws, khoom siv science, thiab bioconjugated chemistry. Nws reactivity rau amines, carboxylic acids, thiab cawv ua rau nws muaj txiaj ntsig reagent rau kev tsim ntawm amides, carbamates, thiab bioconjugates. Raws li kev tshawb fawb hauv cov cheeb tsam no txuas ntxiv mus, diphenylcarbodiimides yuav nyob twj ywm tseem ceeb hauv kev tsim cov ntaub ntawv tshiab thiab cov khoom siv bioactive, pab txhawb kev nce qib hauv ntau yam kev tshawb fawb thiab kev lag luam.