Diphenylcarbodiimide, usoro ọgwụ2162-74-5, bụ ngwakọta nke dọtara mmasị zuru ebe niile na ngalaba nke kemịkalụ organic. Ebumnuche nke isiokwu a bụ inye nkọwa nke diphenylcarbodiimide, njirimara ya, ojiji ya na ihe ọ pụtara na ngwa dị iche iche.
Diphenylcarbodiimide bụ ngwakọta nwere usoro molekụla C13H10N2. kristal siri ike na-acha ọcha ruo na-acha ọcha, na-agbaze ntakịrị na mmiri, na-agbaze ngwa ngwa na acetone, ethanol, chloroform na ihe mgbaze organic ndị ọzọ. A maara ogige a nke ọma maka ike ya iji jee ozi dị ka reagent dị iche iche na njikọ organic, karịsịa na nhazi nke amides na ureas.
Otu n'ime ihe ndị bụ isi nke diphenylcarbodiimide bụ mmeghachi omume ya na amines na carboxylic acid, na-eduga na nguzobe nke amides. A na-akpọ mmeghachi omume a mmeghachi omume njikọ carbodiimide ma na-ejikarị eme ihe na peptide synthesis na biomolecule modification. Tụkwasị na nke ahụ, diphenylcarbodiimide nwere ike imeghachi ihe ọṅụṅụ na-aba n'anya iji mepụta polyurethane, na-eme ka ọ bụrụ ihe bara uru na mmepụta nke ihe polyurethane.
Na ụlọ ọrụ na-emepụta ọgwụ, a pụrụ iji diphenylcarbodiimide mee ka ọgwụ dị iche iche na ndị na-emepụta ọgwụ na-emepụta ọgwụ. Ikike ya ịkwalite njikọ amide bara uru karịsịa maka mmepe ọgwụ peptide na bioconjugates. Ọzọkwa, mmeghachi omume nke ngwakọta ahụ na acids carboxylic na-eme ka ọ bụrụ ngwá ọrụ bara uru maka ijikọta ọgwụ na-elekwasị anya na ụmụ irighiri ihe, si otú a na-eme ka imepụta usoro nnyefe ọgwụ ezubere iche.
Na mgbakwunye na ọrụ ha na nhazi nke organic, a mụọla diphenylcarbodiimides maka iji ha mee ihe na sayensị ihe. Mmeghachi omume nke ogige ahụ n'ebe mmanya na-aba n'anya na-eme ka ọ baa uru na mmepụta nke ụfụfụ polyurethane, mkpuchi na adhesives. Ikike ya ịmepụta polyurethane na-eme ka ọ bụrụ ihe dị mkpa n'ịmepụta ihe ndị na-adịgide adịgide, polyurethane na-agbanwe agbanwe na-eji n'ọtụtụ dịgasị iche iche nke ụlọ ọrụ site na owuwu gaa na ụgbọala.
Mkpa diphenylcarbodiimides gbatịrị na ngalaba bioconjugation na kemịkalụ bioorthogonal. Ejila mmeghachi omume ya na biomolecules mee ihe maka ngbanwe kpọmkwem saịtị nke protein na acid nucleic, na-enyere aka ịmepụta bioconjugates ọhụrụ na nyocha bioimaging. Ọzọkwa, ndakọrịta nke ogige ahụ na gburugburu mmiri mmiri na-eme ka ọ bụrụ ngwá ọrụ bara uru maka ịmepụta mmeghachi omume bioorthogonal iji mụọ usoro ndu na usoro ndụ.
Na nchịkọta, diphenylcarbodiimide, usoro kemịkalụ 2162-74-5, bụ ngwakọta multifunctional nwere ngwa dị iche iche na ngalaba nke njikọ organic, ọgwụ, sayensị ihe, na kemịkalụ bioconjugated. Mmeghachi omume ya na amines, acid carboxylic, na alcohols na-eme ka ọ bụrụ reagent bara uru maka imepụta amides, carbamates na bioconjugates. Ka nyocha na mpaghara ndị a na-aga n'ihu na-aga n'ihu, diphenylcarbodiimides nwere ike ịnọgide na-abụ ndị isi na mmepe nke ihe ọhụrụ na ogige bioactive, na-enye aka na ọganihu dị iche iche na nkà mmụta sayensị na ụlọ ọrụ mmepụta ihe.
Oge nzipu: Mee-27-2024