Diphenylcarbodiimide, chimiro chemakemikari2162-74-5, ikomboni yakakwezva kutarisisa kwakapararira mumunda we organic chemistry. Chinangwa chechinyorwa chino ndechekupa tarisiro ye diphenylcarbodiimide, zvimiro zvayo, mashandisirwo, uye kukosha mukushandisa kwakasiyana.

Diphenylcarbodiimide isanganiswa ine molecular formula C13H10N2. Ichena kusvika kure-chena crystalline yakasimba, inonyungudika zvishoma mumvura, inonyungudika zviri nyore muacetone, ethanol, chloroform uye mamwe maorganic solvents. Mushonga uyu unonyanya kuzivikanwa nekugona kwayo kushanda sechinhu chakasiyana-siyana reagent mune organic synthesis, kunyanya mukuumbwa kwemaamide uye ureas.

Chimwe chezvinhu zvakakosha zve diphenylcarbodiimide kuitazve kwayo nemaamines uye carboxylic acids, zvichitungamira mukuumbwa kwemaamide. Kuita uku kunonzi carbodiimide coupling reaction uye inoshandiswa zvakanyanya mu peptide synthesis uye biomolecule modification. Mukuwedzera, diphenylcarbodiimide inogona kuita nedoro kuita polyurethane, zvichiita kuti ive yakakosha reagent mukugadzirwa kwe polyurethane zvinhu.

Muindasitiri yemishonga, diphenylcarbodiimide inogona kushandiswa kugadzira mishonga yakasiyana-siyana uye yepakati pemishonga. Kugona kwayo kusimudzira kuumbwa kweamide bond kunonyanya kukosha pakuvandudza peptide zvinodhaka uye bioconjugates. Uyezve, kuitazve kwekomboni kune carboxylic acids kunoita kuti ive chishandiso chinobatsira chekubatanidza zvinodhaka kunanga mamorekuru, zvichigonesa dhizaini yeanonangwa dhizaini masisitimu.

Pamusoro pebasa ravo mune organic synthesis, diphenylcarbodiimides dzakadzidzwa kuitira kugona kwavo kushandiswa muzvinhu zvesainzi. Iko kudzokororwa kwekomboni kune madoro kunoita kuti ibatsire mukugadzirwa kwemafuro epolyurethane, machira nemanamira. Kugona kwayo kugadzira polyurethane kunoita kuti ive chinhu chakakosha mukugadzirwa kwezvinhu zvinogara kwenguva refu, zvakasiyana-siyana zvepolyurethane zvinoshandiswa mumaindasitiri akasiyana siyana kubva pakuvaka kuenda kumotokari.

Kukosha kwe diphenylcarbodiimides kunowedzera muminda ye bioconjugation uye bioorthogonal chemistry. Kuitazve kwayo kune mabiomolecules kwakashandiswa kushandiswa kwesaiti-chaiyo shanduko yemapuroteni uye nucleic acids, zvichigonesa kuvandudzwa kweinoveli bioconjugates uye bioimaging probes. Uyezve, kuwirirana kwekomboni nenzvimbo ine mvura inoita kuti ive chishandiso chakakosha chekugadzira bioorthogonal reactions yekudzidza maitiro ebhayoloji mumasisitimu ehupenyu.

Muchidimbu, diphenylcarbodiimide, kemikari formula 2162-74-5, musanganiswa unoshanda wakasiyana-siyana mundima ye organic synthesis, mishonga yemishonga, sainzi yemidziyo, uye bioconjugated chemistry. Kuitazve kwayo kune maamines, carboxylic acids, uye madoro kunoita kuti ive yakakosha reagent yekuumbwa kwemaamide, carbamates, uye bioconjugates. Sezvo kutsvagisa munzvimbo idzi kuri kuramba kuchienderera mberi, diphenylcarbodiimides ingangoramba iri vatambi vakakosha mukugadzirwa kwezvinhu zvitsva uye bioactive komisheni, zvichibatsira mukufambira mberi munzvimbo dzakasiyana dzesainzi nemaindasitiri.