Diphenylcarbodiimide, qaacidada kiimikada2162-74-5, waa iskudhis soo jiidatay dareenka baahsan ee dhinaca kimistariga dabiiciga ah. Ujeedada maqaalkani waa in la bixiyo dulmar ku saabsan diphenylcarbodiimide, alaabteeda, isticmaalkeeda, iyo muhiimada codsiyada kala duwan.
Diphenylcarbodiimide waa iskudhis leh caanaha molecular C13H10N2. Caddaan iyo caddaan-caddaan adag oo adag, wax yar ku milmay biyaha, si fudud ugu milmi kara acetone, ethanol, chloroform iyo dareerayaasha kale ee organic. Xaruntan waxaa sida ugu wanaagsan loogu yaqaanaa awoodda ay u leedahay in ay u adeegto sida reagent-ka badan ee isku-dhafka organic, gaar ahaan samaynta amides iyo ureas.
Mid ka mid ah sifooyinka muhiimka ah ee diphenylcarbodiimide waa fal-celintiisa amines iyo asiidhyada karboxilic, taasoo horseedaysa samaynta amides. Dareen-celintan waxaa loo yaqaan falcelinta isku-xidhka karbodiimide waxaana si weyn loogu isticmaalaa isku-dhafka peptide iyo beddelka biomolecule. Intaa waxaa dheer, diphenylcarbodiimide waxay ka falcelin kartaa aalkolada si ay u sameeyaan polyurethane, taas oo ka dhigaysa reagent qiimo leh wax soo saarka maaddooyinka polyurethane.
Warshadaha dawooyinka, diphenylcarbodiimide waxaa loo isticmaali karaa in lagu sameeyo dawooyin kala duwan iyo dhexdhexaadiyeyaasha dawooyinka. Awoodeeda kor u qaadida samaynta curaarta amide waxay si gaar ah qiimo ugu leedahay horumarinta dawooyinka peptide iyo bioconjugates. Intaa waxaa dheer, falcelinta xarunta ee ku wajahan asiidhyada karboksilic waxay ka dhigaysaa aalad waxtar u leh isku xidhka daawooyinka si loo beegsado molecules, taas oo awood u siinaysa naqshadaynta hababka gudbinta daawada la beegsaday.
Marka lagu daro doorka ay ku leeyihiin isku-dhafka dabiiciga ah, diphenylcarbodiimides ayaa lagu bartay isticmaalka suurtagalka ah ee sayniska qalabka. Falcelinta xarunta ee dhanka aalkolada ayaa ka dhigaysa mid waxtar u leh soo saarista xumbo polyurethane, dahaarka iyo xabagta. Awooddeeda samaynta polyurethane waxay ka dhigaysaa qayb muhiim ah oo ka mid ah samaynta qalabyada poliurethane ee joogtada ah, oo isku dhafan oo loo isticmaalo warshado badan oo kala duwan laga bilaabo dhismaha ilaa baabuurta.
Muhiimadda diphenylcarbodiimides waxay ku fidsan tahay dhinacyada bioconjugation iyo kimistari bioorthogonal. Dareenkeeda ku wajahan biomolecules ayaa looga faa'iidaystay beddelka goobta-gaarka ah ee borotiinnada iyo asiidhyada nucleic-ka, taas oo awood u siinaysa horumarinta bioconjugates cusub iyo baadhitaannada bioimaging. Intaa waxaa dheer, waafaqid xarunta ay la leedahay deegaanka biyaha leh ayaa ka dhigaysa qalab qiimo leh oo lagu horumarinayo falcelinta bioorthogonal si loo barto hababka bayoolojiga ee hababka nolosha.
Marka la soo koobo, diphenylcarbodiimide, qaacidada kiimikada 2162-74-5, waa isku-dhafan kala duwan oo leh codsiyo kala duwan oo ku saabsan dhinacyada isku-dhafka dabiiciga ah, dawooyinka, sayniska agabka, iyo kiimikada bioconjugated. Falcelinteeda dhanka amines, asiidhyada karboxilic, iyo aalkolada waxay ka dhigtaa reagent qiimo leh samaynta amides, carbamates, iyo bioconjugates. Maaddaama cilmi-baarista aagaggani ay sii socoto inay hore u sii socoto, diphenylcarbodiimides waxay u badan tahay inay sii ahaanayaan ciyaartoyda muhiimka ah ee horumarinta walxaha cusub iyo xeryahooda bioactive, iyaga oo gacan ka geysanaya horumarinta dhinacyada sayniska iyo warshadaha kala duwan.
Waqtiga boostada: Meey-27-2024