Diphenylcarbodiimide, foromo ea lik'hemik'hale2162-74-5, ke motsoako o hapileng tlhokomelo e atileng lefapheng la k'hemistri ea lintho tse phelang. Morero oa sengoloa sena ke ho fana ka kakaretso ea diphenylcarbodiimide, thepa ea eona, ts'ebeliso le bohlokoa lits'ebetsong tse fapaneng.

Diphenylcarbodiimide ke motsoako o nang le foromo ea molek'hule C13H10N2. kristale e tšoeu ho isa ho bosoeu bo tiileng, e qhibiliha hanyane ka metsing, e qhibiliha habonolo ka har'a acetone, ethanol, chloroform le metsoako e meng ea tlhaho. Motsoako ona o tsebahala haholo ka bokhoni ba ona ba ho sebetsa e le reagent e feto-fetohang ho organic synthesis, haholoholo sebopehong sa li-amides le ureas.

E 'ngoe ea likarolo tsa bohlokoa tsa diphenylcarbodiimide ke ho sebetsa ha eona hape le li-amine le li-carboxylic acid, tse lebisang ho thehoeng ha li-amides. Karabelo ena e bitsoa carbodiimide coupling reaction mme e sebelisoa haholo ho peptide synthesis le phetoho ea biomolecule. Ho phaella moo, diphenylcarbodiimide e ka itšoara ka joala ho etsa polyurethane, e leng se etsang hore e be reagent ea bohlokoa ha ho etsoa thepa ea polyurethane.

Ka indasteri ea meriana, diphenylcarbodiimide e ka sebelisoa ho kopanya meriana e fapaneng le li-intermediate tsa meriana. Bokhoni ba eona ba ho khothaletsa sebopeho sa amide bond bo bohlokoa haholo bakeng sa nts'etsopele ea lithethefatsi tsa peptide le bioconjugates. Ho feta moo, ts'ebetso ea komporo e lebisang ho li-carboxylic acid e etsa hore e be sesebelisoa se sebetsang sa ho kopanya lithethefatsi ho limolek'hule tse lebileng, ka hona e nolofalletsa moralo oa lits'ebetso tse lebisitsoeng tsa phano ea lithethefatsi.

Ntle le karolo ea bona ho organic synthesis, diphenylcarbodiimides li ithutile bakeng sa tšebeliso ea tsona e ka bang teng ho mahlale a thepa. Boikemisetso ba k'hemik'hale ho lino tse tahang bo etsa hore bo be molemo tlhahisong ea foams ea polyurethane, liphahlo le likhomaretsi. Bokhoni ba eona ba ho etsa polyurethane e etsa hore e be motsoako oa bohlokoa ha ho etsoa thepa ea nako e telele, e nang le mefuta e mengata ea polyurethane e sebelisoang liindastering tse ngata ho tloha kahong ho ea ho likoloi.

Bohlokoa ba diphenylcarbodiimides bo fetela masimong a bioconjugation le bioorthogonal chemistry. Ts'ebetso ea eona mabapi le li-biomolecules e sebelisitsoe hampe molemong oa phetoho e ikhethileng ea liprotheine le li-nucleic acid, e leng ho nolofalletsang nts'etsopele ea li-bioconjugate tse ncha le li-bioimaging probes. Ho feta moo, ho lumellana ha motsoako le libaka tse nang le metsi ho etsa hore e be sesebelisoa sa bohlokoa bakeng sa ho hlahisa maikutlo a bioorthogonal ho ithuta mekhoa ea likokoana-hloko tsamaisong ea bophelo.

Ka kakaretso, diphenylcarbodiimide, foromo ea lik'hemik'hale 2162-74-5, ke motsoako o sebetsang ka mokhoa o fapaneng o nang le lisebelisoa tse fapaneng lefapheng la organic synthesis, meriana, saense ea thepa, le chemistry ea bioconjugated. Reactivity ea eona ho li-amine, carboxylic acid, le alcohols e etsa hore e be sesebelisoa sa bohlokoa bakeng sa ho theha li-amides, carbamates le bioconjugates. Ha lipatlisiso libakeng tsena li ntse li tsoela pele, diphenylcarbodiimides e kanna ea lula e le karolo ea bohlokoa ho nts'etsopele ea lisebelisoa tse ncha le metsoako ea bioactive, e tlatselletsang tsoelopeleng ea mafapha a fapaneng a saense le indasteri.